Definition of myxedema in US English:


(British myxoedema)


  • 1Swelling of the skin and underlying tissues giving a waxy consistency, typical of patients with underactive thyroid glands.

    • ‘The differential diagnosis includes venous stasis dermatitis, pretibial myxedema, filariasis, and ichthyosis.’
    • ‘Patients with myxedema present with rough skin of the palms, soles, elbows and knees, and yellow-orange discoloration of the skin, along with other signs of hypothyroidism.’
    • ‘He supports this with reference to a retrospective analysis of the records of 50 patients with myxoedema.’
    • ‘The presence of goiter, coarse hair, dry skin, carotenemia, and myxedema indicates hypothyroidism.’
    • ‘I changed my hairdresser but the possibility of myxoedema did not enter my head.’
    1. 1.1 The more general condition associated with hypothyroidism, including weight gain, mental dullness, and sensitivity to cold.