Definition of myelodysplasia in US English:



  • 1Abnormal development of the spinal cord, especially in the lumbar or lumbo-sacral region.

  • 2Abnormal development of one or more types of blood cell (erythrocytes, leukocytes, or thrombocytes); any of a group of disorders characterized by this, presenting with anaemia, leukopenia, or thrombocytopenia (or any combination of these), and sometimes progressing to acute myeloid leukaemia.


Early 20th century; earliest use found in American Journal of the Medical Sciences. In sense 1 from German Myelodysplasie.