One of the mysteries of the English language finally explained.
1Attributive and (now rare) in the genitive. Used with reference to a type of lepromin testing developed by Mitsuda; (now) (specifically, especially in "Mitsuda reaction") designating the delayed type of response to lepromin, consisting of nodular infiltration of the skin developing between one and four weeks, and considered to be a measure of cell-mediated immunity.
2In compounds with the sense ‘in regard to the Mitsuda reaction‘, as "Mitsuda-negative", "Mitsuda-positive"; also "Mitsuda positivity".
1930s; earliest use found in International Journal Leprosy. From the name of Kensuke Mitsuda, Japanese leprologist, who described a lepromin test around 1919.
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