Definition of missense in US English:

missense

adjective

Genetics
  • Of, relating to, or designating a genetic mutation that alters a codon to code for a different amino acid, resulting in an amino acid substitution in the protein product of the gene.

Origin

1960s. From mis- + sense, after nonsense.

Pronunciation

missense

/ˈmɪsˌs(ə)ns/