Definition of microsome in US English:

microsome

noun

Biology
  • A fragment of endoplasmic reticulum and attached ribosomes obtained by the centrifugation of homogenized cells.

    • ‘The degradation of calf thymus DNA, an indicator of free iron existence, was observed in the reactions of microsomes obtained from control and baicalein-treated rats with ascorbic acid in the presence of bleomycin.’
    • ‘Intact lysosomes, mitochondria and microsomes were isolated from RPE cells.’
    • ‘These authors, by using differential and density-gradient centrifugation techniques, achieved the differentiation of the microbody fraction from lysosomes, microsomes, and mitochondria.’
    • ‘We attempted to circumvent the need for microsomes by attempting a coupled transcription-translation-import system using freshly purified mitochondria instead of microsomes during the translation reaction.’
    • ‘Exposure of drug-sensitive tumor cells to doxorubicin or epirubicin results in the drugs being localized primarily within the nuclei, with much smaller amounts being localized in plasma membranes, microsomes, and the cytosol.’

Pronunciation

microsome

/ˈmīkrəˌsōm/