Definition of methysergide in US English:

methysergide

noun

Pharmacology
  • A lysergic acid derivative that acts as a selective serotonin receptor antagonist, and is sometimes used, usually in the form of its maleate, for the prevention of severe migraine and cluster headaches; 1-methyl-d-lysergic acid butanolamide, C₂₁H₂₈N₃O₂.

Origin

1960s; earliest use found in American Journal of the Medical Sciences. From meth- (in methyl: see note s.v. meth-) + -yserg- + -ide.

Pronunciation

methysergide

/mɛθɪˈsəːdʒʌɪd/