Definition of metastasis in English:



  • 1The development of secondary malignant growths at a distance from a primary site of cancer.

    • ‘Preoperatively, radiation is delivered to decrease the risk of local recurrence, prevent the development of distant metastasis and reduce tumor size to permit sphincter-preserving surgery.’
    • ‘Patients with a diagnosis of granular cell tumor should have a complete physical examination to exclude other primary tumors or metastasis from an aggressive malignant tumor.’
    • ‘A malignant neoplasm in the neck can arise as a primary tumor or as metastasis from the upper aerodigestive tract or a distant site.’
    • ‘Breast tumors may also be the result of metastasis from primary prostate cancer.’
    • ‘Six years later, a fine-needle aspirate of a cervical vertebra showed malignant cells consistent with metastasis from a primary lung carcinoma.’
    malignant growth, cancerous growth, malignant tumour, tumour, malignancy
    View synonyms
    1. 1.1 A metastatic growth.
      • ‘The purpose of this study was to investigate in detail the pathologic aspects of thyroid cancers with bone metastasis and to compare these with various clinical parameters.’
      • ‘However, only in 3 of these cases was the morphologic appearance in the metastasis so well differentiated as to be considered benign if taken out of context.’
      • ‘This eliminates perverse growth, anticipating the metastasis that is seeking to re-enter the system.’
      • ‘GTP inhibited the levels of urokinase plasminogen activator as well as matrix metalloproteinases 2 and 9, cellular molecules linked to the metastasis.’
      • ‘Sixteen cervical lymph nodes with metastasis of oral cancer and 20 benign lymph nodes were studied.’


Late 16th century (as a rhetorical term, meaning rapid transition from one point to another): from Greek, literally removal or change from methistanai to change.