Definition of mesothelium in US English:


nounPlural mesothelia

  • 1The epithelium that lines the pleurae, peritoneum, and pericardium.

    • ‘This tumor also lacks the ultrastructural features consistent with mesothelium.’
    • ‘By this concept, the mesothelium was originally organized as a simple or stratified myoepithelium with epitheliomuscular cells.’
    • ‘Albumin is considered a good marker of capillary permeability in the pleura, because there is no evidence that albumin is produced or stored in pleural mesothelium.’
    • ‘If present, they represent entrapped benign mesothelium or epithelium.’
    • ‘By in situ hybridization, MnSOD mRNA can be detected in arterioles, septal tips of alveolar ducts, endothelial cells, and in pleural mesothelium of hyperoxia-exposed rats.’
    • ‘Mesothelioma (cancer of the mesothelium) is a disease in which cells of the mesothelium become abnormal and divide without control or order.’
    • ‘These features are reminiscent of the typical mesothelial cells seen in hyperplastic mesothelium regardless of location and that of the epithelioid-type mesothelial cells frequently observed in malignant mesothelioma.’
    • ‘In hetero- and hoplonemerteans investigated there is an ECM layer situated between the vessel lining mesothelium and underlying muscle, which may be part of the general body-wall musculature or an intrinsic musculature.’
    • ‘Mesothelioma is a rare form of carcinoma that occurs in the mesothelium lining lungs, abdomens and hearts.’
    • ‘However, a mesothelial origin of this tumor has been questioned, since these tumors are seen in sites where mesothelium is not found.’
    • ‘The outermost covering of the stomach is termed serosa, because it is composed of a loose fatty connective tissue containing blood vessels and nerves covered by a mesothelium, the visceral peritoneum, or mesentery.’
    • ‘Studies were also conducted to assess the expression of the heavy and light subunits of gamma-GCS in human pleural mesothelium and bronchial epithelium in vivo and the induction of inducible NOS by asbestos fibers.’
    • ‘If the cancer has spread beyond the mesothelium to other parts of the body, symptoms may include pain, trouble swallowing, or swelling of the neck or face.’
    • ‘Macroscopically, they have a thin fibrous wall and contain serous fluid. The gross pathology is confirmed at the microscopic level, where one sees a thin fibrous wall lined by a monolayer of mesothelium.’
    • ‘It does help to distinguish mesotheliomas from reactive, proliferating mesothelium, which typically has no cytogenetic abnormalities.’
    1. 1.1Embryology The surface layer of the embryonic mesoderm, from which this is derived.


Late 19th century: from meso- ‘middle’ + a shortened form of epithelium.