Definition of mesoderm in US English:



  • The middle layer of an embryo in early development, between the endoderm and ectoderm.

    • ‘The stem cell lines also retain the ability, throughout the culture, to differentiate into tissue-derived endoderm, mesoderm and ectoderm.’
    • ‘Teratomas are germ cell tumors composed of various tissue elements representing more than one embryonic layer (ectoderm, mesoderm, and endoderm).’
    • ‘Acrochordons, or skin tags, are derived from ectoderm and mesoderm and represent a hyperplastic epidermis.’
    • ‘Teratoma typically contains tissues derived from all 3 germinal layers, whereas dermoid cyst presumably originates from ectoderm and mesoderm.’
    • ‘A similar pair of parachordal cartilages develop posteriorly from mesoderm, flanking the notochord.’
    • ‘Why is the origin of mesoderm from hypoblast in some groups not regarded as a secondary adaptation?’
    • ‘By the time segmentation is complete, strong mxp expression is detected in both ectoderm and mesoderm of the maxillary and labial limb buds.’
    • ‘We have used experimental manipulation of chick embryos to test the causal role of Hox genes in patterning derivatives of the paraxial mesoderm.’
    • ‘The most affected tissue being dorsal mesoderm; the notochord is disrupted and the tailbud fails to form.’
    • ‘The stem cells for hematopoiesis in mammals are derived from mesoderm in the yolk sac blood islands and a region of the aorta.’
    • ‘Derived from embryonic mesoderm, mesenchyme is the first connective tissue formed.’
    • ‘The mesoderm also provides the mesenchyme (by sinking of cells from its epithelium into the extracellular matrix) from which organ development becomes possible.’
    • ‘Expression is also detected variously in visceral endoderm, and anterior mesoderm and endoderm of the gut and pharynx in some vertebrates and amphioxus.’
    • ‘Endoderm and mesoderm form from the lower layer of cells.’
    • ‘The cells of the visceral mesoderm and dorsal vessel also express both genes.’
    • ‘Clearly the establishment of independent Hox codes in the paraxial and lateral plate mesoderm would have significance for both the development and the evolution of vertebrates.’
    • ‘Structures derived from ectoderm, mesoderm, and endoderm are commonly represented.’
    • ‘Because neoblasts are likely derived from embryonic stem cells, a stem cell system may be even the original mode of mesoderm formation in the embryo.’
    • ‘Crystal cells constitute a class of hemocytes derived from the head mesoderm.’
    • ‘Cells from the ventrolateral dermomyotome migrate away from the midline forming a population of axially derived cells that differentiate within the lateral mesoderm.’


Late 19th century: from meso- ‘middle’ + Greek derma ‘skin’.