Definition of memantine in English:



  • A prescription drug for the treatment of Alzheimer's disease. It protects the brain's nerve cells against glutamate, which is released in excess by Alzheimer's-damaged brain cells.

    Also called Namenda (trademark)
    • ‘As Betsy deteriorates over the next year, adding memantine to her regimen might boost her thinking, improve her behavior and stabilize her ability to do day-to-day tasks, such as brushing her teeth and hair.’
    • ‘The U.S. Food and Drug Administration has approved memantine for treatment of moderate to severe Alzheimer's disease, and it may be used in combination with a cholinesterase inhibitor.’
    • ‘A newer treatment called memantine has recently been launched for people in the middle to late stages of Alzheimer's.’
    • ‘However, because most of the health care costs of Alzheimer's disease relate to advanced disease, memantine may be cost-effective even if the absolute clinical benefits are small. - C.W.’
    • ‘The new data, some of which were reported at a meeting last year, convinced the European Union to add late-stage Alzheimer's disease to memantine's approved uses.’