Definition of malignancy in US English:

malignancy

nounPlural malignancies

  • 1The state or presence of a malignant tumor; cancer.

    ‘after biopsy, evidence of malignancy was found’
    • ‘We found no evidence of malignancy, but dysplastic changes were present in the glandular cells.’
    • ‘She has no evidence of malignancy, inflammatory disease, hemorrhage, or chronic infection.’
    • ‘A 66-year-old woman with no previous history of malignancy presented with melena.’
    • ‘Poor prognostic indicators include poorly responsive disease, delay in diagnosis and the presence of malignancy.’
    • ‘A relatively important, yet underemphasized criterion of malignancy in prostate cancer is the presence of nucleomegaly.’
    • ‘There was no evidence of dysplasia or malignancy.’
    • ‘Cytoplasmic vacuolization in this setting should not be considered evidence of malignancy in men with gynecomastia.’
    • ‘A whole-body bone scan showed no evidence of bony metastases, and a mammogram showed no evidence of malignancy.’
    • ‘Examination of cells under the microscope to identify the presence of malignancy.’
    • ‘Infections must be treated aggressively, and surveillance for unusual infections, malignancy, or autoimmune disease is critical.’
    • ‘Kaposi's sarcoma is the most common skin malignancy associated with HIV infection.’
    • ‘The patient's history of smoking and the initial presentation of malignancy in the lung are compatible with a lung primary.’
    • ‘Presumptive diagnoses ranged from a malignant pleural tumor to malignancy occupying the complete lower lobe.’
    • ‘Meningitis as a presenting symptom of malignancy would be extremely rare.’
    • ‘A previous fine needle aspirate of the thyroid had revealed atypical follicular cells but no obvious evidence of malignancy.’
    • ‘Tumours of high malignancy will sometimes have spread widely before they are diagnosed.’
    • ‘Always consider esophageal malignancy when dysphagia is present.’
    • ‘In these cases, the presence of distant metastasis was a clear sign of malignancy.’
    • ‘The systemic features of both entities can mimic occult infection, malignancy, multiple myeloma and connective tissue disease.’
    • ‘‘Current patients with a diagnosis of malignancy will be admitted at the discretion of medical staff,’ the hospital stated.’
    1. 1.1 A cancerous growth.
      • ‘Alternatively, infiltrating microglia near a focus of radiation necrosis may be mistaken for a malignancy in a treated glioma.’
      • ‘The tumour cells in these malignancies and not the adjacent normal tissues have the evidence of the virus DNA and the virus proteins.’
      • ‘Dr. Folkers began to raise money to pursue his dream of using CoQ10 to treat malignancies.’
      • ‘Tubular adenomas account for 75% of adenomas but comprise only 5% of malignancies.’
      • ‘The examination revealed a cancerous tumour, and a biopsy revealed a malignancy.’
      • ‘When the mutation occurs in a cell, it essentially takes the brakes off the cell's growth, causing a malignancy.’
      • ‘Helicobacter pylori infection has been associated with the pathogenesis of peptic ulcer disease and gastric malignancies.’
      • ‘The cure rate for Hodgkin's disease is high but there is a risk of developing secondary malignancies.’
      • ‘All donors were screened for malignancies, autoimmune and certain neurological disorders, and any high-risk behavior.’
      • ‘None of the patients had endometrial hyperplasia or an underlying malignancy.’
      • ‘Alterations in the expression of retinoid receptors are implicated in human malignancies.’
      • ‘Second nonocular malignancies develop with increased incidence in patients with hereditary retinoblastoma.’
      • ‘Patients with the syndrome should be screened for an underlying malignancy or autoimmune disorder.’
      • ‘There were 18 solid tumors, 11 hematologic malignancies, and 2 of unknown primary.’
      • ‘The patient had no history of a concurrent or subsequent ovarian or pancreatic carcinoma or an invasive malignancy at any site.’
      • ‘Each successive classification of salivary neoplasia holds space for malignancies that defy these classification schemata.’
      • ‘In contrast, tumor cells don't know when to die, thereby exacerbating the uncontrolled growth of malignancies.’
      • ‘Solid malignancies and nonhematologic diseases were classified as high risk.’
      • ‘The test comes down to giving them varying doses of a mutagen or carcinogen and observing whether malignancies develop.’
      • ‘Can prolonged administration of endothelial antiapoptotic agents influence the growth of malignancies?’
    2. 1.2 A form of cancer.
      ‘diffuse malignancies such as leukemia’
      • ‘The most common clinical presentation of urachal malignancy is hematuria, especially in carcinomas.’
      • ‘Among the neoplastic lesions, both primary and metastatic malignancies must be considered.’
      • ‘Squamous cell carcinoma and tumors of lymphoid tissue are the main malignancies of the pharynx.’
      • ‘Breast carcinoma is one of the most common malignancies among women worldwide.’
      • ‘The most urgent diagnosis is retinoblastoma, a malignancy most likely arising from retinal germ cells.’
      • ‘Additionally, atypical lipomas were considered as malignancies.’
      • ‘Carcinoma of the larynx is a rare malignancy in the paediatric age group.’
      • ‘Melanoma affects a younger patient population than many malignancies.’
      • ‘High-grade soft tissue sarcomas are a group of malignancies that often affect otherwise healthy young people.’
      • ‘These findings are especially critical because it is important to distinguish fibroadenoma from malignancies.’
      • ‘With all immunosuppressive treatment regimens, there is an increased rate of malignancies, especially lymphomas.’
      • ‘Patients with this malignancy most often present with a cervical mass from metastatic spread to a lymph node.’
      • ‘Conversely, up to 5% of gastric malignancies are lymphomas.’
      • ‘We included patients with multiple myeloma but excluded other haematological malignancies.’
      • ‘Ewing's sarcoma is a childhood malignancy of bone and soft tissue.’
      • ‘Similarly, workup of the bone marrow for lymphoma and plasma cell malignancies is aided by immunophenotyping.’
      • ‘The commonest malignancies are basal cell carcinoma, squamous cell carcinoma, and melanoma.’
      • ‘And since this group of malignancies primarily affects elderly patients, such a procedure is particularly arduous and sometimes impossible.’
      • ‘One half of these malignancies are rhabdomyosarcomas originating in striated muscle.’
      • ‘In its biologic behavior, desmoplastic fibroma is probably closer to low-grade malignancies than to usual benign lesions of bone.’
      • ‘A child with this malignancy can present acutely with severe dyspnea and, occasionally, superior vena cava syndrome.’
  • 2The quality of being malign or malevolent.

    ‘her eyes sparkled with renewed malignancy’
    • ‘We know we harbor the same malignancy and malice, the same greed and injustice that we detest in others.’
    • ‘By the very nature of what it is, Empires are malignant, not benign though they cloak this malignancy with shallow kindness.’
    • ‘I get angry, but I don't hate because hate causes malignancy in me, not the person I'm hating.’
    rancour, malevolence, vitriol, spite, spitefulness, vindictiveness, malice, maliciousness, malignity, viciousness, nastiness, ill will, ill feeling, animosity, animus, acrimony, acrimoniousness, bitterness, embitterment, embitteredness, sourness, resentment, grudgingness, virulence, antagonism, hostility, bad blood, bile, spleen, gall, enmity, hate, hatred, dislike, antipathy, aversion
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Pronunciation

malignancy

/məˈlɪɡnənsi//məˈliɡnənsē/