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Any of a class of antibiotics containing a lactone ring, of which the first and best known is erythromycin.
- ‘Trials investigating the role of macrolide antibiotic therapy in patients with acute coronary syndromes are inconclusive.’
- ‘If antibiotics are required, one that is active against gram-positive organisms such as penicillinase-resistant penicillins, cephalosporins, macrolides, or fluoroquinolones should be chosen.’
- ‘As with other currently available fluoroquinolone and macrolide antibiotics, QTc interval prolongation has been linked to the use of telithromycin.’
- ‘Oral antibiotic therapy with macrolides and cephalosporines for presumed pneumonia was started, with a favorable response after 5 days of therapy.’
- ‘Methylation does not affect the function of the adenine residue other than to help the organism become less susceptible to the macrolide class of antibiotics.’
Mid 20th century: from macro- + l(actone) + -ide.
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