Definition of macro- in US English:

macro-

combining form

  • 1Large; large-scale.

    ‘macromolecule’
    ‘macronutrient’
    1. 1.1 (used in medical terms) large compared with the norm.
      ‘macrocephaly’
  • 2Long; over a long period.

    ‘macroevolution’

Origin

From Greek makros ‘long, large’.

Pronunciation

macro-

/ˈmækroʊ//ˈmakrō/