Definition of Letterer–Siwe in US English:

Letterer–Siwe

noun

Medicine
  • Attributive and in the genitive. Designating a severe form of histiocytosis occurring mainly in infants and young children in which many organs of the body are affected by the proliferation of Langerhans cells.

Origin

1930s. From the names of Erich Letterer, German pathologist, and Sture August Siwe, Swedish paediatrician, who described the disorder independently in 1924 and 1933, respectively.

Pronunciation

Letterer–Siwe

/ˌlɛt(ə)rəˈsiːvə/