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1A pungent colorless reactive gas, used as an intermediate in chemical synthesis.
- ‘It was reasoned that the free amino groups on lysine and hydroxylysine, known to be present in Type-I collagen, served as the primary nucleophilic sites for the ketene amide intermediate.’
- ‘The structure of the collagen in the tissue may partially mask some of the available nucleophilic amine sites, whereas water may compete with the amines for the reactive ketene amide intermediate.’
- ‘In addition, we showed that a novel, light-activated DAP derivative could, on photolysis, chemically cross-link tissue through the reactions of the ketene intermediate.’
- 1.1 A substituted derivative of ketene.
Early 20th century: from ketone + -ene.
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The definitions of ‘buddy’ and ‘bro’ in the OED have recently been revised. We explore their history and increase in popularity.