Definition of inoculate in US English:

inoculate

verb

[with object]
  • 1Treat (a person or animal) with a vaccine to produce immunity against a disease.

    ‘he inoculated his tenants against smallpox’
    Compare with vaccinate
    • ‘In Milwaukee, the health department says it doesn't have enough vaccine available to inoculate the city's homebound elderly population, for which the flu is particularly dangerous.’
    • ‘Enough vaccine to inoculate everyone in the country against a pandemic strain of flu will be manufactured after the deadly virus breaks out, the Government pledged yesterday.’
    • ‘After an increase in the number of personnel contracting Hepatitis B, a request was made for all members to be inoculated against the disease.’
    • ‘The United Nations said it planned to start immunisation campaigns which would focus on inoculating children under the age of five against measles and meningitis, and women of childbearing age against tetanus.’
    • ‘Army doctors have started inoculating villagers against disease.’
    • ‘Troops were inoculated against expected infectious diseases as well as two agents of biological warfare - anthrax and botulinum toxin.’
    • ‘Vaccination programmes are being carried out in schools to inoculate children who have not been taken to their doctor for the injection.’
    • ‘I'll rest easier knowing I'm inoculated against eradicated diseases like Smallpox.’
    • ‘When we get enough vaccine, a decision will be made whether or not we all ought to be inoculated simply as protection against an extraordinarily unlikely event.’
    • ‘The threat of terrorists waging biological warfare on Britain was starkly underlined last night when the Government announced that it was acquiring enough smallpox vaccine to inoculate the entire population.’
    • ‘In the event of a smallpox outbreak, the federal government is prepared with enough vaccine to inoculate everyone who would need it.’
    • ‘When monkeys were inoculated with the vaccines, the primates' immune systems mounted a response against either the Ebola or Marburg virus.’
    • ‘In desperation, soldiers and citizens took to secretly inoculating themselves for protection.’
    • ‘Among the older children, 19 had been inoculated with measles vaccine.’
    • ‘The children, who are mainly toddlers, could pick up infections and may not after all be inoculated against the childhood diseases, it has emerged.’
    • ‘Fifty years from now the doctors will be inoculating for every conceivable disease.’
    • ‘And he's told me how children would come in and they would inoculate them against diseases, but he knew there had to be something else.’
    • ‘He states that anthrax vaccine is not being produced, but the Pentagon has embarked on a massive effort to produce this vaccine and to inoculate all US troops on active duty.’
    • ‘If we want to prevent someone from catching a serious disease, we inoculate them.’
    • ‘Oftentimes, though, the person being inoculated would contract the disease and suffer its consequences.’
    immunize, vaccinate, inject
    View synonyms
    1. 1.1 Introduce (an infective agent) into an organism.
      ‘the microorganism can be inoculated into laboratory animals’
      • ‘Half of them were randomly chosen to be inoculated with C. campestris (infected group), leaving the rest uninfected (control group).’
      • ‘When inoculated into humans, the weakened bacteria should induce an immune response but not cause disease.’
      • ‘Organisms obtained from these animals, when inoculated into uninfected animals, proved to be unresponsive to atovaquone therapy, suggesting the emergence of drug resistance.’
      • ‘Given their effects on soybean plants, it is hypothesized that the PGPR strains exert their influence via the production of specific compounds after they have been inoculated into plant rhizospheres.’
      • ‘In lymphatic filariasis, infective larvae are inoculated by mosquitoes; adult worms are found in lymph nodes or adjacent lymphatics, and offspring circulate in the blood, often only at night.’
    2. 1.2 Introduce (cells or organisms) into a culture medium.
      • ‘For initial qualitative screening of elevated mutation frequencies in isolates, a single colony of each isolate to be tested was inoculated into 4 ml Luria broth.’
      • ‘For UV exposure, single colonies were inoculated into SC-LEU at 25° for 17 hr.’
      • ‘White colonies were inoculated into 96-well plates.’
      • ‘Test strains were inoculated into heart infusion broth and incubated overnight at 37 deg C.’
      • ‘A purified colony was inoculated into 5 ml of broth and grown overnight before plating dilutions onto LB plates supplemented with 50 g/ml thymidine.’

Origin

Late Middle English (in the sense ‘graft a bud or shoot into a different plant’): from Latin inoculat- ‘engrafted’, from the verb inoculare, from in- ‘into’ + oculus ‘eye, bud’. The sense ‘vaccinate’ dates from the early 18th century.

Pronunciation

inoculate

/iˈnäkyəˌlāt//ɪˈnɑkjəˌleɪt/