Definition of hyperplasia in US English:



Medicine Biology
  • The enlargement of an organ or tissue caused by an increase in the reproduction rate of its cells, often as an initial stage in the development of cancer.

    • ‘No women were found to have endometrial carcinoma or adenomatous hyperplasia with atypia.’
    • ‘Water-clear cell hyperplasia is a rare but well-documented cause of primary hyperparathyroidism.’
    • ‘Such factors might include the presence of benign prostatic hyperplasia or prostate cancer.’
    • ‘Furthermore, increased goblet cell hyperplasia of the small airways was prominent in this model.’
    • ‘Smooth enlargement suggests benign hyperplasia; roughness and irregularity suggest the possibility of cancer.’


Mid 19th century: from hyper- ‘beyond’ + Greek plasis ‘formation’.