Definition of homeodomain in US English:

homeodomain

(also homoeodomain)

noun

Genetics
  • A sequence of 60 amino acids encoded by a homeobox, forming a distinctive structural domain with a DNA-binding function in proteins involved in the regulation of transcription and (less commonly) translation.

Origin

1980s; earliest use found in Cell. From homoeo- + domain.

Pronunciation

homeodomain

/ˈhəʊmɪə(ʊ)də(ʊ)ˌmeɪn/