Definition of Hirschsprung's disease in US English:

Hirschsprung's disease


  • A congenital condition in which the rectum and part of the colon fail to develop a normal system of nerves, and consequently feces accumulate in the colon following birth.

    • ‘The most common associated conditions include Hirschsprung's disease and imperforate anus.’
    • ‘Rarely, vomiting is caused by disordered motility states, the most common of which is Hirschsprung's disease.’
    • ‘In children younger than one year of age, the possibility of Hirschsprung's disease must be considered.’
    • ‘Anorectal manometry is indicated to demonstrate the rectoanal inhibitory reflex and to rule out Hirschsprung's disease.’
    • ‘Children with an organic cause for constipation, such as Hirschsprung's disease, were excluded.’


Early 20th century: named after Harald Hirschsprung (1830–1916), Danish pediatrician.


Hirschsprung's disease

/ˈhirSHpro͝oNGz dəˌzēz/