Definition of hemolytic disease of the newborn in English:

hemolytic disease of the newborn

noun

Medicine
  • A severe form of anemia caused in a fetus or newborn infant by incompatibility with the mother's blood type, typically when the mother is Rhesus negative and produces antibodies that attack Rhesus positive fetal blood through the placenta.

    Also called erythroblastosis
    • ‘While an assistant pathologist at the Hospital, she published papers on haemolytic disease of the newborn.’
    • ‘Fetomaternal hemorrhage leads to alloimmunization of Rh D-negative mothers, resulting in an increased risk of hemolytic disease of the newborn.’
    • ‘In England and Wales, about 500 fetuses develop haemolytic disease each year, and about 25-30 babies die from haemolytic disease of the newborn.’
    • ‘Both anti-C and anti-G are clinically significant antibodies capable of causing extravascular transfusion reactions and hemolytic disease of the newborn.’
    • ‘In addition hemolytic disease of the newborn may be due to antibodies in other blood group system antigens.’