One of the mysteries of the English language finally explained.
- ‘If deleterious mutations tend to be partially recessive, purifying selection is expected to be more efficient on the X chromosome relative to the autosomes, due to haploidy in males.’
- ‘Whether or not any particular deletion can be recovered will, of course, depend upon the phenotypic consequences of haploidy for its chromosome region.’
- ‘The problem was obvious: if the sex of an animal was the result of a balance of male- and female-determining genes on the sex chromosomes and autosomes, how could haploidy give rise to males?’
- ‘One possibility is that natural selection is more efficient on the X chromosome due to effective haploidy of the X chromosomes in males and persistently low effective numbers of reproducing males compared to that of females.’
- ‘Although triploidy and haploidy of chromosomal regions in humans often cause viable or semiviable developmental defects, it is difficult to identify regions of the genome that are haplolethal.’
Top tips for CV writingRead more
In this article we explore how to impress employers with a spot-on CV.