Definition of haloperidol in US English:



  • A synthetic antidepressant drug used chiefly in the treatment of psychotic conditions.

    • ‘He conducted double-blind controlled trials on the important antipsychotic drugs chlorpromazine and haloperidol, and later on antidepressants.’
    • ‘Haloperidol, promethazine, and midazolam are on Rio's list of essential drugs, and haloperidol and promethazine are on the World Health Organization's model list of essential drugs.’
    • ‘Although the use of high potency antipsychotic drugs like haloperidol brings an increased risk of extrapyramidal side effects, the actual reported incidence is low.’
    • ‘Treatment of delirium requires use of neuroleptic drugs, such as haloperidol and chlorpromazine, not sedatives.’
    • ‘Isolated instances of such damage have been reported with such drugs as benoxaprofen, chlorpromazine, haloperidol, imipramine, and others.’


1960s: blend of halogen and piperidine + -ol.