One of the mysteries of the English language finally explained.
Relating to or denoting an environment for rearing or culturing organisms in which all the microorganisms are either known or excluded.
- ‘Recently, however, model systems for examination of the intestinal flora have been made available in the establishment of germ-free, gnotobiotic (known flora) and specific pathogen-free animals.’
- ‘The March 30th issue of the Proceedings of the National Academy of Sciences, with a Warholian zebrafish cover, features a study from Washington U. where the fish were raised under strictly aseptic (gnotobiotic) conditions.’
- ‘The MUSC Gnotobiotic Research Resource gives investigators at MUSC a unique opportunity to conduct research with germfree (gnotobiotic) animal models, in addition to more widely available specific-pathogen-free animal models.’
1940s: from Greek gnōtos ‘known’ + biotic.
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