Definition of glycosaminoglycan in US English:



  • Any of a group of compounds occurring chiefly as components of connective tissue. They are complex polysaccharides containing amino groups.

    Formerly called mucopolysaccharide
    • ‘In the initial phase of these titrations the peptide was much in excess over the added glycosaminoglycan.’
    • ‘Coumarin drugs, such as warfarin as well as the glycosaminoglycans, heparin and heparan sulfate, are useful as anticoagulants.’
    • ‘Two other glycosaminoglycans, namely heparin and chondroitin sulfate B, were also studied with isothermal titration calorimetry.’
    • ‘Heparin is a glycosaminoglycan whose major anticoagulant effect is accounted for by a pentasaccharide with a high affinity for antithrombin III.’
    • ‘This matrix consists of a network of structural and adhesive proteins embedded in a gel of glycosaminoglycans and proteoglycans.’