Definition of glucuronic acid in US English:

glucuronic acid


  • An acid derived from glucose, occurring naturally as a constituent of hyaluronic acid and other glycosaminoglycans.

    A uronic acid; chemical formula: HOOC(CHOH)₄CHO

    • ‘In hepatocytes, UDP glucuronyl transferase adds 2 equivalents of glucuronic acid to bilirubin to produce the more water soluble, bilirubin diglucuronide derivative.’
    • ‘HA is a naturally occurring, linear polysaccharide with repeating disaccharide units composed of glucuronic acid and N-acetyl glucosamine.’
    • ‘It is well-known that the active compound of licorice is glycyrrhizin, a conjugation of two molecules of glucuronic acid and glycyrrhetic acid.’
    • ‘At therapeutic doses, acetaminophen is biotransformed to nontoxic products and eliminated by conjugation with glucuronic acid and sulfate.’
    • ‘We predicted that Mojave woodrats would excrete more glucuronic acid per unit dry mass of resin consumed.’


glucuronic acid

/ˌɡlo͞okyəränik ˈasəd/