Definition of Gaucher's disease in US English:

Gaucher's disease


  • A hereditary disease in which the metabolism and storage of fats is abnormal. It results in bone fragility, neurological disturbance, anemia, and enlargement of the liver and spleen.

    • ‘It is expected to materially change the way in which patients suffering from Gaucher's disease, a disorder of the liver and spleen, will be treated in the future.’
    • ‘But it soon added testing for a range of other conditions that are not always fatal, including conditions that are late-onset or that range in the severity of their expression - such as cystic fibrosis and Gaucher's disease.’
    • ‘He adds that this immune defect may also be present in other diseases where a build-up of waste and plaques occur, such as in cardiovascular disease and Gaucher's disease.’
    • ‘Like them, we are concerned with the increased number of patients with Gaucher's disease who develop pulmonary hypertension.’
    • ‘Gene therapy is feasible, and some preliminary studies have already been carried out in Gaucher's disease.’


Early 20th century: named after Phillippe C. E. Gaucher (1854–1918), French physician.


Gaucher's disease

/ɡōˈSHāz dəˌzēz/