Definition of exergonic in US English:



  • (of a metabolic or chemical process) accompanied by the release of energy.

    The opposite of endergonic
    • ‘In this way, the energy released by the exergonic reaction can be partially harnessed to drive the endergonic one.’
    • ‘Even if a reaction is exergonic (energy-releasing), it may not proceed if its activation energy is too high.’
    • ‘The changes of mechanical power are supported by a sequence of exergonic processes that over the last decades have been the subject of extensive research in biochemistry and biophysics.’
    • ‘In this strongly exergonic reaction, the high-energy phosphate of PEP is conserved as ATP.’
    • ‘With its highly exergonic free energy change, the flow of electrons through Complex I is more than adequate to drive ATP synthesis.’


1940s: from ex- ‘out of’ + Greek ergon ‘work’ + -ic.