Definition of epitope in English:



  • The part of an antigen molecule to which an antibody attaches itself.

    • ‘Even in the case of microbial antigens not found in vertebrates such as lipopolysaccharides, it should be noted that peptide epitopes can mimic bacterial carbohydrates and DNA.’
    • ‘On cell-surface glycoproteins, the epitope structure of TF antigen is linked to either serines or threonines.’
    • ‘The loci of the known epitopes of the antibodies used are shown diagrammatically in Fig.1.’
    • ‘In all the experiments on native titin, the molecule was attached to two beads, each labeled with an antibody to a different epitope.’
    • ‘We chose to consider residue charge because of evidence that the pattern of residue charges is important in determining epitopes for antibodies.’


1960s: from epi- upon + Greek topos place.