One of the mysteries of the English language finally explained.
The part of an antigen molecule to which an antibody attaches itself.Also called antigenic determinant
- ‘In all the experiments on native titin, the molecule was attached to two beads, each labeled with an antibody to a different epitope.’
- ‘The loci of the known epitopes of the antibodies used are shown diagrammatically in Fig.1.’
- ‘Even in the case of microbial antigens not found in vertebrates such as lipopolysaccharides, it should be noted that peptide epitopes can mimic bacterial carbohydrates and DNA.’
- ‘We chose to consider residue charge because of evidence that the pattern of residue charges is important in determining epitopes for antibodies.’
- ‘On cell-surface glycoproteins, the epitope structure of TF antigen is linked to either serines or threonines.’
1960s: from epi- ‘upon’ + Greek topos ‘place’.
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