Definition of encephalopathy in US English:



  • A disease in which the functioning of the brain is affected by some agent or condition (such as viral infection or toxins in the blood).

    • ‘Hypertensive encephalopathy is the syndrome of central nervous system impairment associated with hypertensive crisis.’
    • ‘Neurodegenerative diseases causing transmissible spongiform encephalopathies are the subject of intense research.’
    • ‘Transmissible spongiform encephalopathies such as mad cow disease and its human counterpart, variant Creutzfeldt-Jakob disease, are not caused by bacteria or viruses.’
    • ‘Both mad-cow and mad-deer disease are transmissible spongiform encephalopathies, in which brain proteins called prions deform, forcing other brain cells to degenerate along with them.’
    • ‘This extremely rare and fatal brain disorder belongs to a family of human and animal diseases known as the transmissible spongiform encephalopathies.’
    • ‘Prions are special proteins believed to be the infectious agents responsible for transmissible spongiform encephalopathies, a group of rare, fatal disorders that slowly destroy the brain and nervous system.’
    • ‘Hepatic encephalopathy occurs in patients with portal hypertension and cirrhosis.’