Definition of dipyridamole in US English:


Pronunciation /ˌdīpiˈridəmōl//dīˈpiridəˌmōl/


  • A synthetic drug used as a coronary vasodilator to treat angina, and to reduce platelet aggregation and hence the chance of thrombosis.

    • ‘Antiplatelet drugs, such as low dose aspirin or dipyridamole, are used in patients with bioprosthesis in sinus rhythm and in addition to anticoagulants in the high risk patients with mechanical valves.’
    • ‘Clopidogrel should be used in patients with true intolerance to aspirin (allergy or intractable side effects on low dose enteric coated aspirin with or without antiulcer drugs); dipyridamole alone does not prevent cardiac events.’
    • ‘The fixed-dose combination of extended-release dipyridamole and aspirin combines two antiplatelet agents with different modes of action.’
    • ‘Taking aspirin with dipyridamole reduces platelet accumulation at the anastomosis.’
    • ‘Antiplatelet agents, including aspirin and dipyridamole, should not be given within 72 hours before surgery in patients with end-stage renal disease or uremic chronic kidney disease.’


From di- ‘two’ + pyr(imidine) + (piper)id(ine) + am(ino-) + -ol.