Definition of diabetes insipidus in US English:

diabetes insipidus


  • A disease in which the secretion of or response to the pituitary hormone vasopressin is impaired, resulting in the production of very large quantities of dilute urine, often with dehydration and insatiable thirst.

    • ‘Congenital nephrogenic diabetes insipidus is caused by mutations in the vasopressin receptor or the aquaporin - 2 gene.’
    • ‘Pure water loss is frequently associated with fever, hyperventilation or diabetes insipidus.’
    • ‘A 35-year-old woman was referred to our neurosurgery department with symptoms of hemianopsia, diabetes insipidus, amenorrhea, and a presumptive diagnosis of pituitary tumor.’
    • ‘Patients with intracranial germinoma at other locations may present with diabetes insipidus, hypopituitarism, and Perinaud syndrome.’
    • ‘The vet suggests several lab tests to rule out a urinary tract infection and other more serious diseases such as diabetes mellitus and diabetes insipidus.’


Late 19th century: from diabetes + Latin insipidus ‘insipid’.


diabetes insipidus

/ˌdīəˌbēdēz inˈsipidəs/