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1Cause (someone) to become insane.‘that business last month must have deranged him a bit’
insane, mad, of unsound mind, out of one's mind, not in one's right mind, disturbed, unbalanced, unhinged, unstable, crazed, demented, irrational, berserk, frenzied, maniac, lunatic, psychopathic, certifiable, raving, raving madView synonyms
- ‘You know, this is really a deranged person that would be taking these shots and killing people or injuring people.’
- ‘People think of me as some kind of deranged comedian.’
- ‘You're right Karen, most of my work has involved dealing with bizarre conspiracy theories told by people who often appear completely deranged.’
- ‘But have you seen anything to suggest that he was part of any organized conspiracy, or was he just an isolated, deranged individual?’
- ‘But John was blameless: a happy and healthy family man cut down by a deranged fan on the way home from work.’
- ‘He should not be held responsible for this deranged man's actions.’
- ‘He was a deranged murderer, but he wanted to save us from a government run amok.’
- ‘We are not dealing with some deranged serial killer here, who has no sense of reality.’
- 1.1 Throw (something) into confusion; cause to act irregularly.‘stress deranges the immune system’
- ‘My memory was deranged because of the new program.’
- ‘In addition, antibiotic treatment deranges protective flora and antibiotic resistant microbial strains emerge.’
- ‘In scoliosis, the anatomy is deranged not only at each vertebral level but also between the convex and concave sides of the curve in the spine.’
- ‘It is well known that stress deranges the immune systems of human beings and non-human primates alike.’
- ‘Sometimes the stress deranges the managers' senses.’
- ‘As when an individual soldier lost his balance, many flailing and falling soldiers deranged the enemy formation causing a serious decrease in the enemy's own firepower.’
- ‘In other patients, the genes preparing neurofilament proteins that support the nerve fibers are deranged.’
- ‘The group kicked proceedings off, squeezing their way into hormonally deranged teen hearts, with a crisp and punchy pop-punk-pounce.’
- ‘Autosomal genes often showed deranged regulatory levels, indicating they were in pathways perturbed by X chromosomal changes.’
- ‘Unforeseen accidents may derange our most profound schemes of policy.’
- ‘Several drugs have been shown to derange macrophage functions, bactericidal efficacy and production and secretion of cytokines.’
- 1.2archaic Intrude on; interrupt.‘I am sorry to have deranged you for so small a matter’
throw into confusion, throw into disorder, throw into disarray, cause confusion in, cause turmoil in, play havoc with, turn upside-down, make a mess ofView synonyms
- ‘From her gauze veiling the young woman spoke:-- "We are sorry to derange you. The guard made a mistake. Pardon!"’
Late 18th century: from French déranger, from Old French desrengier, literally ‘move from orderly rows’.
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