Definition of de novo in English:

de novo

Pronunciation: /dā ˈnōvō//di/

adjective & adverb

  • Starting from the beginning; anew.

    [as adverb] ‘in a pure meritocracy, everyone must begin de novo’
    [as adjective] ‘a general strategy for de novo protein design’
    • ‘Both the Federal Reserve and the Office of the Comptroller of the Currency recommend that Congress remove outdated barriers to de novo interstate branching.’

Origin

Early 17th century: Latin, literally from new.

Pronunciation:

de novo

/dā ˈnōvō//di/