Definition of de novo in English:

de novo

adjective & adverb

  • Starting from the beginning; anew.

    as adverb ‘in a pure meritocracy, everyone must begin de novo’
    as adjective ‘a general strategy for de novo protein design’
    • ‘Both the Federal Reserve and the Office of the Comptroller of the Currency recommend that Congress remove outdated barriers to de novo interstate branching.’

Origin

Latin, literally ‘from new’.

Pronunciation

de novo

/di/