Definition of bupropion in US English:



  • An antidepressant drug (C₁₃H₁₈ClNO) that is also given to relieve the symptoms of nicotine withdrawal.

    Also called Zyban (a trademark)
    • ‘What I haven't told you is that this was also a study of a drug called bupropion, trade name Zyban, to see if it works in getting people with schizophrenia to quit.’
    • ‘The antidepressant drug bupropion can help control nicotine cravings.’
    • ‘The combined use of nicotine replacement, bupropion, and social or behavioral support can increase the quit rate to 35 percent.’
    • ‘Nicotine replacement therapy and other interventions, such as the antidepressant bupropion, which should be available in the United Kingdom later this year, double the quitting rate.’
    • ‘Licensed primarily as an antihypertensive, clonidine shares some pharmacological effects with bupropion and tricyclic antidepressants.’


1970s: from butane + propion (see propionic acid) + -n (perhaps from -one).