Definition of biomarker in English:

biomarker

noun

  • A measurable substance in an organism whose presence is indicative of some phenomenon such as disease, infection, or environmental exposure.

    ‘a biomarker that may predict aggressive disease recurrence in liver transplant recipients’
    • ‘It is important to examine other biomarkers, such as chromosome aberrations and micronuclei, that relate to the damage still present after cellular processing.’
    • ‘Protein biomarkers offer great potential to improve the predictivity of animal studies and, in particular, provide the bridge between effects in animals and in man.’
    • ‘In our laboratory we have adapted a similar strategy to that reported by Liu et al. to perform on-line sample dialysis and clean-up for several protein biomarkers.’
    • ‘Moreover, it has helped us identify species and biomarkers that may better contribute to establishing the quality and extent of the toxicological impact.’
    • ‘Plasma concentration of homocysteine is a good biomarker for folate deficiency.’
    • ‘If biomarkers for the disease are present in the patient's sample, the lab-on-a-chip analysis will separate fluorescent antibodies bound to the biomarker from unbound antibodies.’
    • ‘Diet is an important variable in determining DNA damage biomarkers, specifically micronuclei.’
    • ‘Several biomarker studies have examined the impact of vitamin E supplementation on biomarkers of DNA damage.’
    • ‘Several biomarkers for genetic susceptibility which are also associated with increased cancer risk have been identified.’
    • ‘Under such circumstances, the identification of noninvasive or minimally invasive biomarkers of disease activity is essential.’
    • ‘The gene expression biomarkers of caloric restriction can also be used to develop pharmaceuticals targeted to its genomic effects.’
    • ‘In addition, a better integration will facilitate the discovery of genes for novel biomarkers and targets for new therapeutic interventions.’
    • ‘Proteins linked to cancer may then serve as biomarkers to detect early disease and predict responsiveness to therapy or the likelihood of recurrence.’
    • ‘If this were the case, increased intake of beta-carotene would not be expected to protect against disease since it was a biomarker of some other process and not indicative of low dietary intake.’
    • ‘Cytogenetic damage, evaluated as chromosomal aberrations, has been successfully applied as a reliable biomarker for chronic health risk.’
    • ‘Your lab is now searching for biomarkers, proteins in the blood that are linked to the presence of particular cancers.’
    • ‘The effect of isolated soy protein on plasma biomarkers in elderly men with elevated serum prostate specific antigen.’
    • ‘Molecular diagnostics is a branch of clinical diagnostics that uses primarily DNA or RNA as a biomarker for clinical testing.’
    • ‘A variance decomposition analysis was performed to reveal the extent to which platform error influenced the ability to identify biomarkers.’
    • ‘The compounds identified include biomarkers: compounds that can be related to identifiable biological chemical ‘species’.’

Pronunciation:

biomarker

/ˈbīōˌmärkər/