Definition of bioassay in US English:

bioassay

noun

  • Measurement of the concentration or potency of a substance by its effect on living cells or tissues.

    • ‘It should be noted that the mouse toxigenicity bioassay requires up to 4 days to complete.’
    • ‘The following is a position paper challenging the paradigm that ‘carcinogen = mutagen’, and that the current rodent bioassay to predict risks to human cancers is relevant and useful.’
    • ‘In practice, the bacterial mutation test is the most widely used and best validated bioassay for assessment of potentially mutagenic contaminants.’
    • ‘Using the in vitro bioassay of protein synthesis a partial purification of the eyestalk material was obtained.’
    • ‘Identification of botulinum toxin is completed using a mouse neutralization bioassay.’
    • ‘Laboratory bioassay: The shade dried fungus was cut and ground into a fine powder.’
    • ‘This bioassay provides a measure that is precise and repeatable, but more importantly reflects the ecological context of TTX intoxication.’
    • ‘As indicators of insect and mammalian resistance we conducted bioassays to measure the performance of a geometrid moth, Epirrita autumnata, and counted the amount of resin droplets on the shoot of the saplings, respectively.’
    • ‘The bioassay was replicated three times for each plant.’
    • ‘The bioassay, which should reflect a well-defined effect of the androgenic gland on the gonad or on sexual characteristics, should be short and reproducible.’
    • ‘A bioassay was developed to measure specific yolk protein synthesis in vitro.’
    • ‘Thus, the same cotton plants used in the experiments were tested in bioassays for differential effects on an insect herbivore.’
    • ‘Thus they may be motivated to continue to sell drugs even as they desist from use because of the deterrent effect of bioassay screening.’
    • ‘All insecticide concentrations were prepared in absolute alcohol and the larval bioassay was carried out according to the standard WHO procedure.’
    • ‘Green tea has shown remarkable anti-inflammatory and cancer chemopreventive effects in many animal tumor bioassays, cell culture systems, and epidemiological studies.’
    • ‘The germination process was also quantified using an identical germination bioassay with other plant and Orobanche species.’
    • ‘Larvae died with virus symptoms after feeding on treated foliage and the leaf bioassay was easier to count than the apple bioassay.’
    • ‘In addition, a simple and efficient in vitro regeneration bioassay was developed for the preliminary screening of transgenic lines against a pathogenic fungus.’
    • ‘The development of new biological control measures, or those using chemicals that are non-toxic to non-target organisms, requires a suitable and reliable bioassay.’
    • ‘A medium-term liver bioassay for carcinogens can be used for detecting the effect of chemical mixtures at low dose levels, as well as detection of the carcinogenic potential of individual test chemicals.’

Origin

Early 20th century: from bio- ‘life’ + assay.

Pronunciation

bioassay

/ˌbaɪoʊəˈseɪ//ˌbīōəˈsā/