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The failure of an organ or tissue to develop or to function normally.
- ‘Patients undergoing such treatment are at high risk for bone marrow aplasia.’
- ‘At the time of aplasia, the child with sickle cell disease is highly contagious.’
- ‘Further tests, including a bone marrow sample for leukaemia, failed to confirm a diagnosis but the illness was linked to a rare from of pure red blood cell aplasia.’
- ‘Because this disease is virtually always fatal due to the profound bone marrow aplasia, management is not well defined and is rarely successful.’
- ‘Transplants of stem cells from either the same person or another person are used to repopulate and regenerate the bone marrow, ‘rescuing’ the patient from aplasia.’
Late 19th century: from a- without + Greek plasis formation.
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