Definition of antipsychotic in US English:



  • attributive (chiefly of a drug) used to treat psychotic disorders.

    • ‘In this respect, treatment strategies that minimise the risk of side effects, such as the use of low dose typical neuroleptics or atypical antipsychotic drugs, may be a rational choice for the first episode.’
    • ‘Our review identified only five trials evaluating use of oral atypical antipsychotic drugs to treat the behavioural and psychological symptoms of dementia.’
    • ‘Some investigators believe that antipsychotic drugs should be used only for the management of psychotic features that cause patients ‘serious distress.’’
    • ‘He conducted double-blind controlled trials on the important antipsychotic drugs chlorpromazine and haloperidol, and later on antidepressants.’
    • ‘Akathisia has been well documented as a common and distressing side effect of antipsychotic drugs and an important cause of poor drug compliance.’
    • ‘This suggests that the actions are not mediated via the impact of the antipsychotic drug on psychotic symptoms alone.’
    • ‘The use of new antipsychotic medications for the treatment of schizophrenia and bipolar disorder is beginning to create a whole new set of problems for patients taking these drugs.’
    • ‘Although the use of high potency antipsychotic drugs like haloperidol brings an increased risk of extrapyramidal side effects, the actual reported incidence is low.’
    • ‘I have fought off an attempt to section me under the Mental Health Act, and I have taken a battery of antidepressant / antipsychotic drugs that left me desperately tired and sick.’
    • ‘The third set included only patients taking antipsychotic drugs and used haloperidol as the reference.’
    • ‘The prevalence of sexual dysfunction in men and women treated with antipsychotic drugs is high; however, the contribution of hyperprolactinaemia and secondary hypogonadism needs to be determined.’
    • ‘The large majority of people with schizophrenia show substantial improvement when treated with antipsychotic drugs.’
    • ‘Antianxiety agents, antidepressants and antipsychotic drugs can be highly beneficial for many.’
    • ‘Treatment of schizophrenia in most cases involves a combination of antipsychotic medications and psychosocial therapy.’
    • ‘Fortunately for Lawrence and John, that same piece points to success in treating racism with antipsychotic drugs.’
    • ‘Patients treated with some antipsychotic medications have been shown to be at increased risk for ventricular arrhythmias, cardiac arrest, and sudden death.’
    • ‘Hoey said camp doctors are treating some detainees for psychological disorders and have administered antidepressants and antipsychotic drugs.’
    • ‘The pharmacodynamic action of atypical antipsychotic drugs is attributed to their action on both the serotonergic and dopaminergic systems.’
    • ‘The manic episodes of bipolar disorder are often treated using antipsychotic drugs (sometimes called neuroleptics).’


  • An antipsychotic drug.

    • ‘People taking atypical antipsychotics can be compared with either people taking an alternative antipsychotic or with those prescribed no antipsychotic drugs.’
    • ‘The drug has a pharmacologic profile unlike standard antipsychotics and is labeled as an atypical antipsychotic.’
    • ‘The drug list included all available antidepressants, antianxiety agents, antipsychotics, and anticonvulsants.’
    • ‘Most patients on admission were on high levels of psychotropic medication, particularly antidepressants, antipsychotics and mood stabilisers.’
    • ‘Could early lawsuits against antipsychotics have had a stifling effect on developing clozapine?’
    • ‘Table 1 summarizes the effects of various antidepressants and antipsychotics on libido.’
    • ‘Antiepileptics, antipsychotics, and anxiolytics are drugs that may be used as sedatives.’
    • ‘The use of antidepressants, antipsychotics, or anticholinesterase inhibitors for insomnia related to delirium or dementia is also unproved.’
    • ‘At the time of decompensation, 23 patients were taking antipsychotics while 16 were drug free.’
    • ‘Effects are increased when benzodiazepines and antipsychotics are used in combination.’
    • ‘How this drug compares with other newer antipsychotics remains to be established.’
    • ‘These included mothers who took antipsychotics, other antidepressants, or antianxiety medications.’
    • ‘Newer antipsychotics such as clozapine, risperidone and olanzapine have less side-effects.’
    • ‘The most commonly used drugs are antidepressants, mood stabilizers and antipsychotics.’
    • ‘Our data show that the risk of ischaemic stroke is similar for patients receiving atypical antipsychotics and those receiving typical antipsychotics.’
    • ‘The authors point out that prolactin sparing atypical antipsychotics offer a new management strategy for antipsychotic induced hyperprolactinaemia.’
    • ‘Atypical antipsychotics are more expensive than the conventional drugs.’
    • ‘Most patients were receiving antidepressants and antipsychotics on admission.’
    • ‘The drugs used for schizophrenia are antipsychotics or neuroleptics (major tranquillizers).’
    • ‘The newer antipsychotics that drug makers introduced in the 1990s allegedly cause fewer neurological side effects.’