Definition of antidepressant in US English:



  • (chiefly of a drug) used to alleviate depression.

    • ‘In the more severe cases, tranquilizers and antidepressant drugs have been reported to be of benefit.’
    • ‘Q. Can you become depressed while taking an antidepressant drug like Zoloft?’
    • ‘In this paper we refer mainly to conditions of unipolar depression that are considered severe enough to warrant treatment with antidepressant medication.’
    • ‘People with both major or less severe depression often respond well to antidepressant medication.’
    • ‘Psychiatrists are experienced in prescribing the different types of antidepressant medication, and in spotting their side-effects.’
    • ‘The review of the evidence highlights associations between the severity of depression and response to antidepressant medication.’
    • ‘The other main category of antidepressant drugs is the tricyclic drugs.’
    • ‘As many as 35 percent of older patients do not respond to antidepressant medications.’
    • ‘We examined whether a combination of problem solving treatment with antidepressant medication is more effective than either treatment alone.’
    • ‘As primary treatment it is somewhat more successful and safer than the very effective antidepressant drugs.’
    • ‘A large and rapidly growing number of antidepressant medications are effective against depression.’
    • ‘A common issue in the treatment of patients with depression is compliance with antidepressant drug regimens.’
    • ‘If you are experiencing major depression, however, your doctor may prescribe antidepressant medication to treat it.’
    • ‘These include amphetamines, antidepressant drugs, caffeine, corticosteroids and lithium.’
    • ‘Treatment of individuals suffering from depression using antidepressant medications appears to be on the rise.’
    • ‘Studies have shown that exercise can be almost as effective as antidepressant medication for some people.’
    • ‘I got antidepressant pills from my GP, he was given a research post.’
    • ‘Urologists do sometimes prescribe antidepressant medications such as Prozac, Zoloft or Paxil.’
    • ‘It surely does not automatically equate to merely prescribing antidepressant medications.’
    • ‘A second model excluded usage data for non-narcotic analgesic and antidepressant medications.’


  • An antidepressant drug.

    • ‘Concern surrounds the use of tricyclic antidepressants in patients with cardiovascular disease.’
    • ‘The most commonly used drugs are antidepressants, mood stabilizers and antipsychotics.’
    • ‘A quarter of the new drugs now being developed by pharmaceuticals are antidepressants.’
    • ‘The panellists decided to place the warning on all antidepressants rather than single out individual drugs.’
    • ‘Most patients were receiving antidepressants and antipsychotics on admission.’
    • ‘Data that discredit such old drugs may serve well in marketing the new generation of antidepressants.’
    • ‘Other pharmacological options include antidepressants and benzodiazepines.’
    • ‘Further relief of symptoms may be achieved with tricyclic antidepressants and anticonvulsants.’
    • ‘They might interact with some antidepressants and beta-blockers.’
    • ‘No subject in the study was being treated with antipsychotics or antidepressants.’
    • ‘Patients taking tricyclic antidepressants had no increased risk of upper gastrointestinal bleeding.’
    • ‘They might interact with other drugs that cause drowsiness such as alcohol, and some antidepressants.’
    • ‘The treatment drugs of choice are anticonvulsants and tricyclic antidepressants.’
    • ‘Short term use of antidepressants and lithium and hypnosis offer limited help.’
    • ‘Antispasmodic drugs and antidepressants work for some patients but not for others.’
    • ‘Few think that it should be treated with drugs, and most think that antidepressants are addictive.’
    • ‘Various analgesics, vitamins, tranquillisers, and antidepressants had had no effect.’
    • ‘There was a significant correlation between the prescribing of antidepressants of all types and antiulcer drugs.’
    • ‘Another drug trial looks at the efficacy of two antidepressants in the treatment of painful polyneuropathy.’
    • ‘We have assessed risk only relative to people receiving tricyclic antidepressants.’
    tonic, restorative, reviver, energizer, refresher
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