Definition of anastrozole in US English:



  • A nonsteroidal aromatase inhibitor used in the treatment and prevention of breast cancer. It has been observed to have fewer adverse side effects than tamoxifen.

    • ‘Much of the success for the development of tamoxifen, goserilin, and anastrozole in the treatment of early or metastatic breast cancer can be attributed to Ian's ceaseless energy and zeal.’
    • ‘The Food and Drug Administration approved anastrozole for cancer treatment in 1996, and another drug letrozole in 1997.’
    • ‘Consultant oncologist Dr David Fennelly, who is a member of the Irish Cancer Society's Medical Committee, said anastrozole was a valuable addition to existing drugs for the treatment of breast cancer.’
    • ‘The ATAC study is an international collaboration which compared the safety and efficacy of tamoxifen with anastrozole alone and the combination of both drugs for 5 years.’
    • ‘Perhaps we could get rid of 70% of breast cancer by using anastrozole as a preventive therapy.’