One of the mysteries of the English language finally explained.
An acidic compound obtained by the oxidation of uric acid and isolated as an efflorescent crystalline hydrate.
Chemical formula: C₄H₂N₂O₄
- ‘Experimental diabetes mellitus was induced by IV injection (caudal vein) of alloxan monohydrate at a dose of 50 mg/kg body weight.’
- ‘His less successful projects included an attempt to discover a tooth-dye so fashionable ladies could match their smiles to their other accessories and a scheme for synthesizing alloxan - essential to lipstick - from python-droppings.’
- ‘In a study of rats given alloxan to induce diabetes, both water and alcohol extracts of fenugreek had some hypoglycemic activity.’
- ‘Since alloxan destroys pancreatic beta-cells, it was presumed that fenugreek either stimulated insulin release from remaining beta-cells or had insulin-receptor activity.’
- ‘To investigate the molecular mechanism underlying the effects of oxidative stress on plant growth reorientation, the effects of alloxan on isolated leaf protoplasts were studied.’
Mid 19th century: from all(antoin) + ox(alic) + -an.
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