One of the mysteries of the English language finally explained.
The presence of homogentisic acid (alkapton) in the urine; an inherited (autosomal recessive) metabolic disorder characterized by this, and by ochronosis and arthritis, especially of the spine.
Late 19th century. From alkapton + -uria, perhaps after German Alkaptonurie.
In this article we explore how to impress employers with a spot-on CV.