Definition of agranulocytosis in US English:

agranulocytosis

noun

Medicine
  • A deficiency of granulocytes in the blood, causing increased vulnerability to infection.

    • ‘In the United Kingdom the drug may only be prescribed by registered consultant psychiatrists; this reflects the serious adverse effect profile of the drug, which includes agranulocytosis.’
    • ‘When reviewers repeated the trial years later, in a larger population, they found the incidence of this agranulocytosis was much lower than previously thought.’
    • ‘None of the patients on the drug developed agranulocytosis.’
    • ‘The latter one leads to agranulocytosis; hence monitoring blood investigations is necessary.’
    • ‘Routine monitoring of white cell counts remains controversial, but results of one study showed that close monitoring of white cell counts allowed for earlier detection of agranulocytosis.’

Origin

Early 20th century: from a- + granulocyte + -osis.

Pronunciation

agranulocytosis

/āˌɡranyəlōsīˈtōsəs/