One of the mysteries of the English language finally explained.
- ‘Pharmacologically, it is characterized by the constitutive activity of the ligand-free receptor, and by the inverse, partial, and full agonism due to the bound ligand.’
- ‘An agonist is described as a drug that binds to and activates receptors; the possibility of spontaneous receptor activity and therefore of inverse agonism is not mentioned.’
- ‘Rather, all known abused drugs affect a limited number of neurotransmitters by agonism or antagonism of a specific receptor site.’
- ‘Studies have clearly demonstrated that key therapies in the acute attack of migraine share the common pharmacologic activity of serotonin receptor agonism.’
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