One of the mysteries of the English language finally explained.
Any kind of pill formulated from several ingredients (with different actions) and used in the treatment of diseases believed to affect more than one system or part of the body, or to be caused by more than morbid humour.
Early 17th century; earliest use found in Thomas Lodge (1558–1625), author and physician. After post-classical Latin pillula aggregativa; compare the French and Spanish parallels cited in the main etymology.
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