Definition of adenylate cyclase in English:

adenylate cyclase

(also adenyl cyclase)

noun

Biochemistry
  • An enzyme that catalyzes the formation of cyclic adenylic acid from adenosine triphosphate.

    • ‘The response of cells to the binding of glucagon to its cell surface receptor is the activation of the enzyme adenylate cyclase which is associated with the receptor.’
    • ‘In unstimulated ORNs, both adenylate cyclase and cAMP phosphodiesterase are active.’
    • ‘The cAMP is produced by adenylate cyclase, and that enzyme is activated by phosphorylated IIA Glc.’
    • ‘When epinephrine contacts a cell membrane, it triggers the allosteric activation of adenylate cyclase, the enzyme that creates cAMP. cAMP then allosterically activates a protein kinase.’
    • ‘In isolated cilia and in intact olfactory receptor neurons, studies have shown basal activities of both adenylate cyclase and cAMP phosphodiesterase.’

Pronunciation:

adenylate cyclase

/əˈdenl-it//əˈdenlˌāt ˈsīˌklās//-ˌklāz/