Definition of Addison's disease in US English:

Addison's disease


  • A disease characterized by progressive anemia, low blood pressure, great weakness, and bronze discoloration of the skin. It is caused by inadequate secretion of hormones by the adrenal cortex.

    • ‘In people with Addison's disease, the adrenal cortex is destroyed, leading to a deficiency or absence of the hormones it produces.’
    • ‘Licorice has also been found to be effective in the management of Addison's disease or adrenal failure.’
    • ‘I was very fortunate to be in the care of the doctor who diagnosed Addison's disease when he came to visit me at home.’
    • ‘Relative, rather than absolute, leukocytosis occurs in a number of clinical situations, such as infancy, viral infections, connective tissue diseases, thyrotoxicosis and Addison's disease.’
    • ‘It is also prescribed as a replacement hormone in Addison's disease, and for people whose adrenal glands have been removed.’
    • ‘Hyperthyroidism causes a pattern of hyperpigmentation similar to that in Addison's disease, especially in patients with darker complexions.’
    • ‘He is, however, most famous for introducing the first effective treatment for Addison's disease.’
    • ‘It may be a tonic for treating hypoglycemia and Addison's disease and in purifying the liver and bloodstream.’
    • ‘Systemic symptoms may indicate the presence of hyperthyroidism, Addison's disease, or diabetes-related disorders.’
    • ‘Addison's disease affects one in 200,000 women, and causes hormonal problems that can result in weight loss, muscle weakness, fatigue and low blood pressure.’
    • ‘They also treat life-threatening conditions such as Addison's disease, in which the adrenal glands don't produce enough steroids, and help prevent organ rejection in transplant recipients.’
    • ‘Patients with hypothyroidism may have other autoimmune diseases such as type 1 diabetes, Addison's disease, or pernicious anaemia.’
    • ‘For example, in the case of Addison's disease, lack of cortisol causes an increase of pigment in the skin, making the patient appear to have a tan.’
    • ‘Apart from this and Addison's disease, which seemed to be well controlled with a packet of salt a day, he was a well man.’
    • ‘The cause of death was Addison's disease, (adrenal insufficiency) extremely rare in children and virtually unheard of in children under 10 years old.’
    • ‘He had Addison's disease, a failure of the adrenal glands, and needed daily cortisone shots and dangerous steroids in order to combat it.’
    • ‘For many years, licorice has been known to relieve the symptoms of Addison's disease, but only recently have researchers begun to study and understand its interaction in the human body.’
    • ‘Though a master of prose and observation, Austen did not receive much acclaim by the time she died of Addison's disease in 1817.’
    • ‘He was diagnosed as having Addison's disease 40 years ago, when blood tests were more expensive and less frequently used for general screening than they are now.’
    • ‘Suffering from Addison's disease, diabetes and hepatitis C, Gagnon says the pot helps her eat and sleep regularly.’


Mid 19th century: named after Thomas Addison (1793–1860), the English physician who described the disease.