Definition of acetylcholinesterase in English:



  • An enzyme that causes rapid hydrolysis of acetylcholine. Its action serves to stop excitation of a nerve after transmission of an impulse.

    • ‘Both teas inhibited the activity of the enzyme acetylcholinesterase, which breaks down the chemical messenger, or neurotransmitter, acetylcholine.’
    • ‘All nerve agents act by inhibiting the enzyme acetylcholinesterase, which breaks down the neurotransmitter acetylcholine.’
    • ‘Sage oil inhibits an enzyme called acetylcholinesterase, whose normal job is to break down the chemical messenger acetylcholine.’
    • ‘Once released, ACh must be removed rapidly in order to allow repolarization to take place; this step, hydrolysis, is carried out by the enzyme, acetylcholinesterase.’
    • ‘An early favorite target was the vital enzyme acetylcholinesterase, required for hydrolysis of acetylcholine at neuromuscular junctions, and it has been exploited by agrochemical companies in a spectacular manner.’