Definition of Syracuse in US English:

Syracuse

proper noun

  • 1A port on the east coast of Sicily; population 124,083 (2008). It became a flourishing center of Greek culture, especially in the 5th and 4th centuries BC under the rule of Dionysius I and II. It was taken by the Romans at the end of the 3rd century BC.

    Italian name Siracusa
  • 2A city in New York State, to the southeast of Lake Ontario; population 138,068 (est. 2008). The site of salt springs, it was an important center of salt production during the 19th century.