Definition of Hashimoto's disease in US English:

Hashimoto's disease


  • An autoimmune disease causing chronic inflammation and consequential failure of the thyroid gland.

    • ‘She should also rule out an autoimmune disease called Hashimoto's disease, which blocks the release of thyroid hormones, and a pituitary gland problem, because both disorders have symptoms that resemble hypothyroidism.’
    • ‘Deborah Doniach was part of a ground-breaking team that showed that Hashimoto's disease of the thyroid was caused by autoimmunity.’
    • ‘She was also diagnosed with major depressive disorder, type II diabetes and early stage Hashimoto's disease (a thyroid disorder).’
    • ‘In Hashimoto's, antibodies react against proteins in the thyroid gland, causing gradual destruction of the gland itself, and making the gland unable to produce the thyroid hormones the body needs.’
    • ‘In the hypothyroidism of Hashimoto's disease there is autoimmune destruction of thyroid follicular cells, leading to underproduction of the hormones and eventually to thyroid failure.’


1930s: named after Hakaru Hashimoto (1881–1934), Japanese surgeon.


Hashimoto's disease

/ˌhaSHiˈmōdōz diˌzēz/